9) Great examples. Student’s test was used to test the comparability of means, and the 2 sample Wilcoxon rank sum tests were utilized to assess medians. 10.) "there is always more people with the potential for greatness than there are opportunities to be great." It’s true. Chi-squared tests were employed to evaluate proportions. two-tailed values of p. In the case of Augustus I do not believe this. (Given Caesar’s assassination.) Mark Anthony was a real expert in power games.

Ethics acceptance. And even if he’d been defeated by another it is extremely unlikely that they would have done the same thing as Augustus did. All women provided an informed consent to be part of the study. Rome was in deep trouble, in deep trouble. The ethical approval was given to the Ethics Committee of The Faculty of Tropical Medicine, Mahidol University, Thailand (MUTM 2009-011-03) and by the Oxford Tropical Research Ethics Committee, Oxford University, UK (48-08). If you’ve been reading regarding evolution in the past, you might have heard of the concept of "punctuated equilibrium".

Results. It’s the concept that changes happen very slow most of the time However, big changes can occur in a flash. Between the 20th of April 2009 to 19th April 2012 Between the 20th of April and 19th of April 2012, 196 cases of EONS were detected.

Contrary to Darwin’s original theories It doesn’t require the time of an important change to occur – but timing alone isn’t enough. One newborn, who was that was born on the family farm, passed away before he was eligible to be accepted. It requires an appropriate stimulus at the right time and in particular, the appropriate stimulus in the midst of severe stress (environmental change, as in instances of the evolution).

Five additional infants who had the clinical requirements to diagnose EONS were found to be EONS on a an additional review of the clinical record and seven infants showing clinical indications of EONS could not be included since they had already been with antibiotics (because because at-risk factors EONS and not the clinical manifestations in sepsis). Some species who are fortunate that they have correct mutations lurking within their genes undergo rapid changes in gene frequencies that is accompanied by massive phenotypic change to adjust to the changes. There were 183 infants who were recruited to the study.

Other species die out. Nine (5 percent) of them were chosen in error because they didn’t meet eligibility criteria. When the environmental conditions are stable, the species get refined, however their basic nature remains unchanged. The remaining 174 infants will be discussed further (Figure 1. ). For instance, sharks are thought to be the same in the present as they were century ago. The summary includes EONS cases between April 2009 and April, 2012 Maela Camp and enrolment into the study. When the environment is rapidly changing the result is of rapid adaptation or the possibility of death. Early-onset neonatal sepsis.

The end of the Cretaceous period, dinosaurs went extinct, however the bird and mammal species quickly expanded in a huge number. In total, there were 4173 live births in mothers receiving antenatal treatment with SMRU throughout the study and a rate for medically-diagnosed early onset neonatal sepsis (EONS) of 44.8 in thousand live births (187/4,173, 95 percent of the interval 38.7-51.5). Certain individuals, who had the correct mutant genes were considered to be among the "great people" in the Cretaceous. There were spikes in the prevalence of EONS in the months of March and April of each year, when they were the hottest times of year (Figure 2. ). The other species may might have had genetic mutations that would have created a different future, perhaps massive arachnids flying to the stars 10 million years ago.

The number of EONS episodes for each 1000 live births per the month in which the diagnosis was made (primary axis with straight line). But they didn’t. Monthly mean temperature (secondary axis; die-shaded line). The issue is that none of these genes regardless of the species, had any difference prior to the impact. Infant characteristics. The phenotypical traits they displayed were not useful, and more, there was no reason to believe that any major change in phenotype would have any benefit.

Of the infants who were enrolled of the program, 96% (55.2 percent) had male. The existing species were adept at adapting towards the later Cretaceous and any significant changes could have been as ridiculous as Creationist absurdity, such as trying to compare the evolution of birds to the process of bolting ironing boards to a vehicle. The median gestation time was 39 + 5 months (range 30-plus 5-6 to 41+6); 10/174 (5.8 percent) of babies who were prematurely born (>28 between 36 and 6-weeks). In reality, the "great human" genes were far more useless, they threatened the life of each person carrying them.

The median weight of birth is 3.17 grams (range 1.42 between 1.42 and 5.08 kg), 12/172 (7.0 7.0%) were tiny to gestational age. In the history of mankind, there have been (so so far) no external injuries like asteroids. Most of the babies that were included were born at the SMRU hospital, with only a few having been delivered at their homes (5/174, 2.9%) or in Mae Sot hospital (3/174, 1.7 percentage). However, there are still crucial places where everything can depend on the decisions of a great person and vice versa. Sepsis that is early-onset and occurs in neonates. There are much longer times when the equilibrium remains steady. The median age at which patients were admitted to SCBU in patients who had been diagnosed with EONS was one calendar day (range from 0 to five days).

Perhaps Augustus helped save Rome (you probably are more knowledgeable about that time than me) However, why wasn’t Spartacus ruin it? As far as we can tell, Augustus surely had the characteristics of a great person. The most frequent reason for enrolling in the study was temperature of more than 38degC (Table 1. ). However, the world was at a point that his potential – his mutant gene, to use a term could not have a chance of success in expressing. Table 1. The rebellion that was so remarkable initially but was quickly swept away without leaving a trace. Clinical characteristics of 174 neonates identified with EONS and enrolled in the study. *I know that external disturbance isn’t the equivalent to the instability of chaos however, I believe that this illustration still holds. Clinical feature : Number in infants* ( percent) Temperature >38degC 104 (59.8) >37.5degC at two occasions, separated by at-least one hour. (37.9) Perfusion issues (5.9) Poor perfusion (2.9) The respiratory distress is 15 (8.6) Persistent the glucose imbalance (1.7) Abdominal dilation (2.) Abdominal distension (1.2) Abdominal distension 2 (1.2) Bilious aspirates (1.7) In the stool of an infant 1 (0.6) You will notice that I’m not debating the significance of great men completely. *Some babies featured more than one feature , hence the that the total number is higher more than 174.

But I do believe that their power has diminished over time not because the human race is at a steady equilibrium, but because of diverse reasons. Only 5/174 (2.9 percentage) infants displayed at least two clinical manifestations of EONS. Thanks for explaining your thought process here. One these infants also had temperature greater than 38degC.

Concerning Spartacus Concerning Spartacus: I’ve not studied him in detail however I’ve been reading about him in context many times and I do not agree with your opinion. In the infants who had an temperature greater than 38degC 8/104 (7.7 percent) also displayed additional clinical signs of sepsis. I believe Spartacus’s "mutant gene" (as you describe it) was expressed in a remarkable way. Of the infants who had temperatures essays >37.5degC twice, 14/66 (21.2 percent) had additional symptoms of sepsis. He just didn’t have enough (experienced/trained) troops. So 147/174 (84.5 percent) of cases of EONS were diagnosed with fever only.

Also, the timing wasn’t right. Investigations. Roman civilization-economy, manpower, and morale-was still quite sturdy at that particular time. Blood tests were positive for 40/171 patients and in 39 cases (22.8 percent) the results were believed to be contamination. If Spartacus performed the actions he took several decades later, during the turbulent years prior to Augustus" the emperor’s arrival, who knows what could have transpired.

Escherichia coli was found in one blood sample (1/171; 0.3%). This, basically is what I’m trying to convey. The median volume of blood sampled in blood cultures was 0.8 milliliters (SD 0.5 mg). Spartacus played his part at one of the periods and places when the equilibrium was very strong, or even major disruption rapidly subsided to the status as a matter of fact.

A total of 135 punctures to the lumbar region were completed successfully (77.6 percent of all babies being enrolled). I would say that the vast majority of societies, for the majority of time, in the majority ways, have been quite stable. Of the 135 punctures 130 patients, 130 had a blood cell count done and 13 (10.0 percent) had the WBC count of more than 50×10 9 /L.

There are times when an unintentional nudge at just the right time could have enormous and unpredictably negative consequences for the distant future, even if in the moment nothing appears to change. There was a pattern of CRP levels that were significantly higher in these infants when compared with those with an CSF WBC with E. This is an excellent source for "what could have been if" historical speculations, such as what would have happened now should George Washington had had a son. The DNA of E. coli was identified in three different samples (one that was taken from the infant in which E. This is also a common behavior of dynamic systems that are complex. "Chaos" from James Gleick is a good layman’s introduction to the non-linear system’s behavior.